https://novapublishers.com Publisher of Books and Journals in Medicine and Health, Science and Technology and Social Sciences Tue, 14 Feb 2023 19:54:00 +0000 en-US hourly 1 https://wordpress.org/?v=6.1.1 https://novapublishers.com/wp-content/uploads/2018/08/cropped-nova-favicon-32x32.jpg https://novapublishers.com 32 32 https://novapublishers.com/shop/the-biochemical-guide-to-hormones/ Fri, 23 Dec 2022 19:46:02 +0000 https://novapublishers.com/?post_type=product&p=141630 David Aebisher, PhD, DSc - Medical College of The University of Rzeszów, University of Rzeszów, Rzeszów, Poland Series: Endocrinology Research and Clinical Developments BISAC: MED027000 DOI: 10.52305/AEZF7790 This book aims to provide scientific information about hormones. Hormones are chemical compounds that transmit specific information between organs and thus regulate the body's work. As a group of biologically active signaling molecules, they belong to the four main groups of organic chemical compounds. The 36 chapters present the characteristics of exemplary hormones. The prepared monograph is a description of the most popular hormones. In this volume, one can read about the biochemical pathways of adrenaline, adrenocorticotropic hormone (ACTH), aldosterone, antidiuretic hormone (vasopressin), cholecystokinin, corticosteroid, corticotropin releasing hormone (CRH), cortisol, endocrine disorders, endocrine system, epinephrine, erythropoietin, estrogen, follicle-stimulation hormone (FSH), ghrelin, glucagon, gonadotropin releasing hormone (GnRH), growth hormone (GH), growth hormone releasing hormone (GHRH), hepcidin, human chorionic gonadotropin-β, humoral factors, importance of a correct hormonal balance for the psychological well-being of women, insulin, insulin-like growth factor (IGF), luteinizing hormone (LH), insulin, oxytocin, parathyroid hormone (PTH), progesterone, prolactin, thyroid-stimulating hormone (TSH), serotonin, thyroid hormone, thyrotropin releasing hormone (TRH) and prolactin. **Order the printed version and SAVE 50% on the e-book with Print+eBook. Price indicated includes shipping**]]> https://novapublishers.com/shop/understanding-and-managing-hyperthyroidism/ Wed, 19 Oct 2022 17:31:53 +0000 https://novapublishers.com/?post_type=product&p=143068 Karunakaran Poongkodi, MCh, PhD - Senior Civil Surgeon & Assistant Professor of Endocrine Surgery, Principal Investigator, ICMR Extramural Scheme, Government Mohan Kumaramangalam Medical College, Salem, Madras Medical College, Chennai, India Series: Endocrinology Research and Clinical Developments BISAC: MED027000; MED014000; MED000000 DOI: 10.52305/HCEE6098 This book is a must-read to obtain a comprehensive understanding of all aspects of hyperthyroidism, and is a useful practical guide in decision-making in the management of hyperthyroidism as it sheds light on all modalities of treatment such as medicine, nuclear medicine, and surgery, including minimally invasive surgery. **Order the printed version and SAVE 50% on the e-book with Print+eBook. Price indicated includes shipping**]]> https://novapublishers.com/shop/alpinia-nigra-gaertn-burtt-prospects-in-controlling-diabetes/ Thu, 30 Jun 2022 19:42:14 +0000 https://novapublishers.com/?post_type=product&p=126140 Biman Bhuyan - Assistant Professor, Department of Pharmaceutical Sciences, Dibrugarh University, India Angkita Baruah, M Pharm. - Department of Pharmaceutical Sciences, Dibrugarh University, India Prakash Rajak, PhD - Assistant Professor, Department of Pharmaceutical Sciences, Dibrugarh University, India Series: Herbs and Herbalism BISAC: HEA011000; TEC072000 DOI: https://doi.org/10.52305/MYKP9991 This book is an illustrative account on the usage of Alpinia nigra (Gaertn) Burtt. in the traditional medicinal system and its subsequent systematic validation and experimental standardization with special emphasis on its prospects in controlling diabetes. It tries to cover the basic aspects regarding the phytocomposition, pharmacopoeial standardization, in vitro and in vivo studies aimed in verification of its use in the traditional system of medicine. The work embedded in the book successfully upheld the folkloric claims by traditional practitioners in the treatment of diabetes. **Order the printed version and SAVE 50% on the e-book with Print+eBook**]]> https://novapublishers.com/shop/natural-products-for-treatment-of-metabolic-syndrome/ Thu, 09 Jun 2022 19:38:38 +0000 https://novapublishers.com/?post_type=product&p=124881 Ajmer Singh Grewal, PhD - Associate Professor, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India Ashwani Kumar Dhingra, PhD - Professor, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India Series: Endocrinology Research and Clinical Developments BISAC: HEA039160 DOI: https://doi.org/10.52305/FODR8697 Metabolic syndrome (MetS) is a ubiquitous problem that is alarming the world with high prevalence. MetS, also known by other names including syndrome X, insulin resistance syndrome, and dysmetabolic syndrome, constitutes a group of disorders associated with the metabolism of biomolecules and is characterized by hypertension, insulin resistance, cardiovascular diseases, dyslipidaemia, obesity, etc. The pathophysiology of MetS is presumed to involve genetic as well as lifestyle factors including dietary habits, physical activity and perhaps interrupted sleep patterns. The lack of effective prevention and treatment has major effects on the health and lifespan of individuals. As a result, the most challenging task for global researchers is to develop potential lead molecules for the management of MetS with minimal side effects. Weight loss, physical exercise, and healthy diet can help prevent or reverse MetS. A variety of natural compounds are indispensable for the effective management and treatment of MetS. For many years, these natural compounds have provided the basis for development of diverse new classes of potent molecules. This book comprises 6 sections containing 27 chapters written by leading researchers in the field, covering a broad range of topics related to the pathophysiology and possible treatment of MetS with natural products.]]> https://novapublishers.com/shop/polycystic-ovary-syndrome-causes-diagnosis-and-management/ Fri, 16 Apr 2021 14:02:10 +0000 https://novapublishers.com/?post_type=product&p=95309 Katherine Webb (Editor) Series: Endocrinology Research and Clinical Developments BISAC: MED027000 This work contains three chapters, each examining the hormonal imbalance disease polycystic ovary syndrome (PCOS) from a different perspective. Chapter 1 describes various characteristics of PCOS and reviews recent approaches for treatment strategies, including antioxidant supplementation, anti-inflammatory agents, and lifestyle modification. Chapter 2 reviews possible health risks and complications of PCOS. Finally, Chapter 3 aims to provide an understanding and wider concept of pathogenesis and intricacy of various pathways pertaining to the heterogeneity of this syndrome that can help to comprehend the disease’s progression in detail.]]> https://novapublishers.com/shop/diabetes-and-diabetic-complications-current-status-and-future-perspectives/ Mon, 15 Mar 2021 16:00:23 +0000 https://novapublishers.com/?post_type=product&p=93894 Series: Endocrinology Research and Clinical Developments BISAC: MED027000 Diabetes mellitus is one of the major causes of morbidity and mortality in the modern world. Persistent hyperglycaemia is responsible for several complications of diabetes, such as diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, diabetic cardiomyopathy, diabetic autonomic neuropathy, diabetic ketoacidosis, diabetic foot ulcer, gestational diabetes, and diabetic mastopathy. With the advancement of technology, several new drugs have been developed for treatment of diabetes and diabetic complications. Moreover, alternative and complementary medicines have also been employed to manage diabetes and its associated complications. Despite the availability of a plethora of therapeutic agents, the management of diabetes and diabetic complications is an uphill battle associated with several limitations. Various leading research groups across the world are investing billions of dollars to develop impeccable solutions for the treatment of diabetes and diabetic complications. This book focuses on the understanding of recent advancements in the pathogenesis of diabetes and diabetic complications, the molecular basis of the disease and recent advancements in diabetic treatment. The chapters are specifically dedicated to different complications associated with diabetes. Moreover, recent advances in treatments and medications in clinical trials for these complications are explained. Some chapters are dedicated to the use of herbal medicines, alternative and complementary therapy and personalized medicines. Furthermore, the role of epigenetics in diabetic complications is described, as well as the role of antidiabetic drugs and their interactions. Due to its widespread prevalence, diabetes is presently considered a pandemic. This book provides contemporary information to researchers and health care practitioners about diabetes and diabetic complications, which may pave the way for designing new strategies to manage diabetes and diabetic complications. Moreover, the insights on alternative and complementary medicines will help in providing a background for inclusion of these medicines as an important therapeutic option for treatment of diabetes.]]> https://novapublishers.com/shop/gestational-diabetes-from-diagnosis-to-treatment/ Tue, 11 Aug 2020 18:59:46 +0000 https://novapublishers.com/?post_type=product&p=83988 (Series: Endocrinology Research and Clinical Developments BISAC: MED031000 Gestational diabetes, because of its not only high prevalence but also resulting complications in both mother and fetus makes it one of the most important problem of a pregnant woman. The exact cause of gestational diabetes is unknown. Obviously, there is no one reason for the development of the disease. Placental hormones likely play a role. Insulin resistance is in the center and some factors like adipokines, lipids, inflammation, oxidative stress, heavy metals, gut microbiota, autoimmunity, metabolomics, genetic factors and vitamin D are the determinants for the development of insulin resistance and disease itself. Worldwide distribution of the disease changes according to geography. Ethnic factors also play role. Although some well-known risk factors have role in the development of the disease, 1 in 20 women without any risk factors also develop GDM. There is no universal screening and diagnostic methods. Some countries use universal screening some others prefer selective screening of women with risk factors. In addition, some suggest use of one-step diagnosis, while others two-step. The most challenging issue is use of some biomarkers in early (first trimester) diagnosis of pregnancy to prevent development of GDM. Many modalities are used in treatment. Medical nutrition therapy is still the basis of management. Exercise has some roles, too. Besides pharmacotherapies like insulin and oral antidiabetics, some modern modalities like insulin pump therapy together with continuous glucose monitoring, telemedicine, dietary supplements like myoinositols are also covered in this book. Monitorization is important in diabetes and role of nurses in follow-up is incontrovertible. If not treated well, both fetus and mother are open to complications. From congenital malformations to macrosomia, if inevitable, proper management of these problems has to be considered. Some comorbidities like hypertension, thyroid problems and psychosocial stress complicate the problem further. Fetal monitorization, time and type of delivery and management of glycaemia during peripartum period are the issues to be considered towards to end of pregnancy. The problem does not finish with the birth of baby. Both mother and newborn has to be followed for the development of future problems like postpartum diabetes and obesity. Nutrition and benefits of breastfeeding are important points for the health of the baby. In addition, every efforts has to be spent to prevent recurrence of the disease in subsequent pregnancies. The most important instrument against fighting a disease is information i.e. how much we know about it. Understanding the problem thoroughly strengthens our hands to cope and overcome it more easily. The main target of this book is to handle every aspect of the disease from diagnosis to treatment as evident from the title. It is a candidate for a reference guide in this subject. It includes most recent and update data on gestational diabetes.]]> https://novapublishers.com/shop/neurochemistry-of-metabolic-diseases-lysosomal-storage-diseases-phenylketonuria-and-canavan-disease-3rd-edition/ Thu, 16 Jul 2020 16:29:52 +0000 https://novapublishers.com/?post_type=product&p=80055 Sankar Surendran (Editor) College Station, TX, US Series: Metabolic Diseases - Laboratory and Clinical Research BISAC: MED027000 Metabolic disorder caused by altered levels of metabolism resulting pathophysiological abnormalities often leads to childhood death. Several new developments on metabolic diseases research have been emerging. Gaucher disease is a lysosomal storage disorder caused by glucocerebrosidase gene mutations resulting glucocerebrosidase deficiency. Current studies show that the same gene mutations also contribute to the Parkinson’s disease. Tetrahydrobiopterin (BH4) has been widely used in treating patients with Phenylketonuria over a decade. Recent studies reveal that patients treated with BH4 over one-year period showed reduced levels of serum B12, folate and iron intake and therefore patients under chronic BH4 treatment needed to be advised to have additional micronutrients along with BH4. Macrocephaly was used as one of the important features to diagnose Canavan disease. However, a recent study showing a child with aspartoacylase gene mutation developed microcephaly. Hence, Canavan disease phenotype can be either macrocephaly or microcephaly. These are a few examples of recent developments on metabolic diseases research. Therefore, this book was aimed to compose current developments on metabolic diseases research for the use by broad spectrum of experts including Physicians, Neuroscientists, Neurologists, Biomedical researchers, Biochemists, Molecular biologists, Basic Science Researchers and Medical Students. ]]> https://novapublishers.com/shop/estrogen-receptors-structure-functions-and-clinical-aspects/ Thu, 18 Jun 2020 15:07:49 +0000 https://novapublishers.com/?post_type=product&p=75248 George G Chen, Michael CF Tong, and CA van Hasselt (Editors) Department of Otorhinolaryngology, Head and Neck Surgery , Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong Series: Endocrinology Research and Clinical Developments BISAC: MED027000 This 8-chapter book is written by experts from China, Mexico, Portugal, United Kingdom and the United States of America. The book is focused on estrogen receptor structure, functions and clinical significance. Though we are unable to address all aspects of the estrogen receptors, we have analysed and discussed estrogen receptors or their isoforms in some major estrogen receptor-related disorders including cancers, endocrine diseases, respiratory diseases and obesity. The information provided by this book should aid our understanding the role of estrogen receptors in human diseases. This book will be of great value not only for clinicians interested in estrogen receptor-related diseases but also for basic scientists working in the field of estrogen receptors.]]> https://novapublishers.com/shop/medicinal-plants-for-the-treatment-of-metabolic-disorders-part-3/ Thu, 16 Apr 2020 14:40:03 +0000 https://novapublishers.com/?post_type=product&p=73506 Series: Renal, Metabolic and Urologic Disorders BISAC: MED027000, MED004000 This book provides a complete review of multiple metabolic disorders and the use of phytochemicals for their prevention and treatment. When describing each metabolic disorder, all authors describe the main health alterations, providing the most current figures and statistics worldwide; medicinal plants used in traditional medicine for its treatment and scientific information related to their potential to prevent or treat each condition. Authors also include a complete scientific background check, comprehensive analysis of all phytochemicals recommended for each disorder, a description of the mechanism(s) of action and in vivo and/or in vitro studies. Within this volume, a series of 7 plant species, recommended to treat or prevent the previously described disorders, are presented with their botanical information, traditional use in different cultures and countries, and the available scientific information validating their health benefits. Besides, six main metabolic disorders are described, providing a full scientific background for its general understanding, and three study cases are presented, where metabolic disorders are analyzed and approached from different medical and pharmaceutical angles. Chapter 1 – Soybean contains a great nutritional value, which makes it an excellent food for the human diet. It has large amounts of protein and lipids and also provides fiber, calcium, iron, zinc, and several vitamins. For these reasons, the possible benefits of soy consumption for human health have been studied. Although the results obtained to date have not been conclusive, thanks to its high content of isoflavones (phytochemicals with estrogenic activity), soy is attributed with anti-inflammatory, antioxidants and antifungals properties. Moreover, soybeans could provide significant benefits to patients with cardiovascular diseases, cancer, or diabetes. Chapter 2 – Oil, proteins, vitamins, fibers, and phytochemicals present in the avocado plant have shown the excellent capability of not only addressing the prevalence of these metabolic diseases but also being safe and having minimal side effects. The general objective of this book chapter is to review the bioactive compounds and their action to promote health benefits in the prevention and management of metabolic disorders. Chapter 3 – Heliopsis longipes roots, which contain affinin, has been used in traditional cuisine as a spice for its pungent. Due to its tingling and numbing properties, it is frequently applied to heal diverse pains such as toothache, earache, and headache. Within this chapter, its applications on anti-inflammatory activity, local anesthetic, analgesic, anti-mutagenic, and antioxidant activity, will be reviewed. Chapter 4 – The species Opuntia ficus-indica (L.) Mill., represents a good source of nutrients and antioxidants in the diet of consumers. This chapter aims to offer a simple and economical alternative formulation of artisan conserves prepared with nopal, in which the antioxidant activity was evaluated. Chapter 5 – Metabolic syndrome is known as a group of metabolic abnormalities that increase the risk of developing cardiovascular diseases and type 2 diabetes. The cost of health for companies is very high for workers who have obesity or metabolic syndrome compared to healthy workers. Metabolic syndrome is closely related to obesity, and this, in turn, is associated with a poor diet (high intake of carbohydrates and fats). This chapter explains the decrement of risk factors in workers of Young Living Ecuador Farm based on the Health Belief Model. Chapter 6 – The objective of this chapter book was to analyze the evidence obtained by clinical studies reported by scientific literature. Clinical studies have employed different components or products of grapes, such as pulp, freeze-dried grape, extracts, wine, and a distinct dose of resveratrol, to demonstrate their biological properties against diabetes mellitus, hypertension, and obesity. Chapter 7 – The main purpose of this chapter is to describe the analysis of whether glycated hemoglobin values could be used as a limit marker for earlier diagnosis of type 2 DM in overweight patients. This was a nonexperimental, analytical, retrospective, longitudinal study of 100 overweight patients diagnosed with type 2 DM. The study was carried out in 2014 at Teodoro Maldonado Carbo Hospital, Guayaquil, Ecuador. Chapter 8 – Rosemary is classified not only as spice or ornamental but also as a medicinal plant. It is an important source of volatile and non-volatile compounds. The proportion of them varies in function of diverse factors as a region of growth, environment, extraction treatment, and others. Thanks to its composition, rosemary owners several properties such as anti-obesity, anti-diabetes, anti-cancer, among others, thus the importance of this plant over metabolic diseases is presented in this chapter. Chapter 9 – Agave has been used in traditional medicine as an anesthetic, anticonvulsant, antipyretic, urinary antiseptic, cathartic, cicatricial, and regenerative, diuretic, emmenagogue, and eupeptic. Agave extracts and derived agave products have been used to prevent several metabolic diseases, such as diabetes and cancer. However, more studies are needed to support these effects. (Imprint: Nova Medicine and Health)]]> https://novapublishers.com/shop/medicinal-plants-for-the-treatment-of-metabolic-disorders-part-2/ Thu, 16 Apr 2020 14:33:53 +0000 https://novapublishers.com/?post_type=product&p=73503 Series: Renal, Metabolic and Urologic Disorders BISAC: MED027000, MED004000 This book provides a complete review of multiple metabolic disorders and the use of phytochemicals for their prevention and treatment. When describing each metabolic disorder, all authors describe de main health alterations, providing the most current figures and statistics worldwide; medicinal plants used in traditional medicine for its treatment and scientific information related to their potential to prevent or treat each condition. Authors also include a complete scientific background check, complete analysis of all phytochemicals recommended for each disorder, a description of the mechanism(s) of action and in vivo and/or in vitro studies. Within this volume, a series of 3 plant species, recommended to treat or prevent the previously described disorders, are presented with their botanical information, traditional use in different cultures and countries, and the available scientific information validating their health benefits. Besides six main metabolic disorders are described, providing a full scientific background for its general understanding, and three study cases are presented, where metabolic disorders are analyzed and approached from different medical and pharmaceutical angles. (Imprint: Nova Medicine and Health)]]> https://novapublishers.com/shop/ethnicity-and-syndrome-x/ Thu, 09 Apr 2020 15:08:04 +0000 https://novapublishers.com/?post_type=product&p=73304 Mithun Das, PhD (Editor) Associate Professor, Department of Anthropology and Tribal Studies, Sidho-Kanho-Birsha University, Purulia, West Bengal, India Kaushik Bose, PhD, DSc (Editor) Professor, Department of Anthropology, Vidyasagar University, Midnapore, West Bengal, India Series: Endocrinology Research and Clinical Developments BISAC: MED027000 The syndrome X or metabolic syndrome may be defined as a constellation of several interrelated risk factors of metabolic origin which includes centrally distributed obesity, decreased high density lipoprotein cholesterol, elevated triglycerides, elevated blood pressure and hyperglycemia. Persons with syndrome X are at twice the risk of developing cardiovascular disease, and are at about five-fold the risk of type 2 diabetes mellitus as compare to persons with this syndrome. There are considerable evidences of important ethnic differences in the prevalence of syndrome X, its components and sequelae. The prevalence varied between ethnic groups even within the same geographical location. Apart from multifactorial (genetic vs. environmental) nature, there are intriguing metabolic and anthropometric differences found across different ethnic groups. The estimates vary by ethnicity, for instance, high prevalence in non‐European groups such as Black African‐Caribbeans, Hispanics, indigenous populations of North America, South Asians, and the Western Pacific Region and lower prevalence in Chinese populations, and European‐White. Public health strategies that are well known to be important for chronic disease prevention in general can substantially reduce the prevalence of syndrome X. Population-specific studies will be important in identifying subgroups for which syndrome X is a health issue and for which disease management strategies are needed. Simultaneously, studies to identify different biomarkers associated with syndrome X that are linked with the development of specific chronic diseases, such as CVD and diabetes, will significantly enhance the early detection of these diseases. Existing preventions strategies, if implemented in population subgroups at highest risk, may have a substantial effect on reducing these trends. The prevalence of syndrome X increases with advancing age suggests that the efforts to increase awareness of prevention strategies must begin early. Intensive treatment and effective targeting efforts would help in avoiding future sequelae of syndrome X across different ethnicity. This book will be an assemblage of similarities and differences in the risk of syndrome X and related disorders among different ethnic groups worldwide, and reviews potential mechanisms for ethnic differences. It would certain help in translational research for early intervention and better prevention of syndrome X and its associated public health burden worldwide. (Imprint: Nova Medicine and Health)]]>